Once I read the caption I can only see the bag of popcorn now. The effect is gone

I didn’t say it was magic. Part of the issue is we don’t know what modifications he made in making his artificial version. I won’t pretend like there aren’t a lot of unknowns there. It could alter the effectiveness in numerous ways.

Having a heterozygous deletion is still effecting the right gene. Without knowing both of her parents genetics it’s hard to say if it was natural. What he did could produce either a heterozygous or homozygous result on the gene, but only the homozygous presentation is effective at prevention.

So 1 was a full success and the other showed activation on the appropriate gene, but not enough to confer resistance. Although it is possible it does since he used an artificial gene. We know the natural one is not effective in a heterozygous presentation. I still think that was his greatest mistake. He should have just used the naturally effective gene.

You do make a good point with the full backing rigor of the scientific method this procedure would always be successful.

Per the wikipedia page it states that it is not clear if it effective because they’re not going to intentionally infect the children to test it. But we see the results specifically on the targeted gene. That’s a success and demonstrates the technology works.

I’d argue the folly was inserting an artificial gene as opposed to the natural gene that we already know works. Either way the technology showed expression on the correct gene, that is a success.

We’d be having a better discourse on this if his results weren’t banned from every journal and not studied.

By all accounts what he did worked. The potential to end HIV is huge. The amount of human suffering that could be reduced by rolling out what he did is very real.

The technology is here. It’s better to strictly manage it for the public good than to lock it away.

That’s why I’m here

And to keep the private tax filing agencies afloat

Oddly enough it kinda does. OT can make you pay out more taxes on that one check since withholdings are calculated by check. Basically the government/payroll system thinks you’re going to be making that every week so more taxes will be taken out.

In reality this only effects the size of your tax bill or return at the end of the year.