I’m back on my BS is also a solid contributor

The online play is garbage. I played in H1 tournaments around the US back when it was good and would love for them to do it better than they did with their remake. The remake actually remade Halo 1 PC, not the Xbox version.

Me

Sorry, but this makes clear that you aren’t in science. You should avoid trying to shit on studies if you don’t know how to interpret them. Both of the things you mentioned actually support the existence of a true effect.

First, if the treatment has an effect, you would expect a greater rate of relapse after the treatment is removed, provided that it treats a more final pathway rather than the cause: People in the placebo group have already been relapsing at the typical rate, and people receiving treatment–whose disease has been ramping up behind the dam of a medication preventing it from showing–are then expected to relapse at a higher rate after treatment is removed. The second sixth-month period was after cessation of the curcumin or place; it was a follow-up for treatment-as-usual.

Second, people drop out of a study nonrandomly for two main reasons: side effects and perceived lack of treatment efficacy. The placebo doesn’t have side effects, so when you have a greater rate of dropout in your placebo group, that implies the perceived treatment efficacy was lower. In other words, the worst placebo participants are likely the extra dropouts in that group, and including them would not only provide more degrees of freedom, it would theoretically strengthen the effect.

This is basic clinical trials research knowledge.

Again, I have no skin in the game here. I don’t take curcumin, nor would I ever. I do care about accurate depictions of research. I’m a STEM professor at an R1 with three active federal grants funding my research. The meme is inaccurate.

Why are you completely ignoring the second paper I linked, which doesn’t suffer from any of the limitations you mentioned?

The meme says no trial was successful. Any trial with any small difference is a successful trial.

I’m not saying the study is good, just that the meme isn’t true.

Also, you can level almost every single one of those criticisms against many studies for SSRIs and they’d hit just as hard. The exception being sample size.

Not true:

https://www.sciencedirect.com/science/article/pii/S0165032714003620

https://www.cghjournal.org/article/S1542-3565(06)00800-7/fulltext

I found more, too.

Edit: I have no skin in this game. I don’t take turmeric and won’t ever because of the risk of lead. I’m just pointing out that the meme is inaccurate. The person who replied to me pointed out some flaws in the first study (not the second), but none of the flaws mentioned makes the meme accurate. Even the shitty first study I linked found a significant condition difference in its primary endpoint at 8 weeks. Yeah, it’s got flaws (which the second doesn’t), but a successful trial with heavy limitations and conflicts of interest is nonetheless a successful trial, making this meme inaccurate. The second study I linked is stronger.

Also, the limitations in the first trial are standard for many clinical trials. For example:

https://onlinelibrary.wiley.com/doi/abs/10.1111/jsr.12201

https://www.sciencedirect.com/science/article/pii/S0924977X14001266

I could list 100 more with the same limitations of the first study I linked above. High dropout, small sample sizes, funding by an industry with a conflict of interest etc. are standard for clinical trial studies.

That’s not actually the abstract; it’s a piece from the discussion that someone pasted nicely with the first page in order to name and shame the authors. I looked at it in depth when I saw this circulate a little while ago.

That’s fascinating, and I agree with you. Why the US hates the idea of high-speed rail is beyond me, especially because they prided themselves so much on the rail system they put together earlier in their development. In any case, the US can’t do much of anything with its debt-to-GDP as high as it is right now. They can hardly keep from shutting the government down entirely because they won’t even agree to a government budget.

Also, the US is 9.14 million sq. km of land, whereas the EU is 4.29 million sq. km of land

EU is still smaller

But the main reason the US can’t handle the same stuff at a federal level that the EU can is population density. The US government can’t afford to nationalize rural healthcare given how rural the US can be–especially with their debt/GDP at the moment. Give it another few hundred years and the US might catch up to Europe in that respect.

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I’m thinking of shorting it. My friend is definitely shorting it.

To a degree. The large subreddits, like AskReddit, get far fewer upvotes on the top posts of the week than they used to get. I think there’s a good chunk of folks who left for a replacement, then left their replacement without going back to Reddit.

I go out of my way not to do so. Whenever I search for some specific items and see “Sponsored,” I’ll scroll down until I get the same listing without the ad link.

Would you, after devoting full years of your adult life to the unpaid work of learning the requisite advanced math and computer science needed to develop such a model, like to spend years more of your life to develop a generative AI model without compensation? Within the US, it is legal to use public text for commercial purposes without any need to obtain a permit. Developers of such models deserve to be paid, just like any other workers, and that doesn’t happen unless either we make AI a utility (or something similar) and funnel tax dollars into it or the company charges for the product so it can pay its employees.

I wholeheartedly agree that AI shouldn’t be trained on copyrighted, private, or any other works outside of the public domain. I think that OpenAI’s use of nonpublic material was illegal and unethical, and that they should be legally obligated to scrap their entire model and train another one from legal material. But developers deserve to be paid for their labor and time, and that requires the company that employs them to make money somehow.

I’m so in the minority here, but I have a different perspective.

I worked at a grocery store for years, with about a third of my job being cart duty. I loved it when people left their carts outside of the corrals, for a few reasons.

First, if a lot of people did so, I would point it out to whoever was the manager on at the time before I went outside. My manager knew that I would take longer before coming back in, and that would give me more time to stroll/relax/enjoy the outdoors before coming back in to customer craziness. Having those extra minutes because my manager didn’t know how long I should take was nice.

Second, sometimes I had to walk way the hell out to the edge of the parking lot, which was really nice for a long walk away from customer craziness. Such walks were very nice when the weather was nice.

Third, it was job security. Working during the recession made my managers want to let as many people go as they could, but customers who made it so even the most efficient cart duty workers took a while to clear the lot effectively kept more of us employeed than management would have employed otherwise.

For those reasons, whenever the weather is nice, I try to leave my cart in a weird spot that is anchored by something. I realize that many other cart duty folks probably dislike me for it, but I know I appreciated it when others did this. So I do it for the folks like me.

I know all of the arguments against it and I’m not trying to debate here. Just sharing a different perspective; sometimes, leaving your cart in a terrible spot can be nice for some of the workers.

Wow, a real, live, tankie!

Wow, a real, live tankie!

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